Constant denaturant capillary electrophoresis

Khrapko K, Hanekamp JS, Thilly WG, Belenkii A, Foret F, Karger BL (1994) Constant denaturant capillary electrophoresis (CDCE) A high resolution approach to mutational analysis. Nucleic Acids Res 22 364-369. 

The most widely used genetic screening technique, PCR-RFLP detects a mutation at a specific restriction endonuclease cleavage site at the mutation locus [9], The products from other techniques such as ARMS (amplification refractory mutation system), SSCP (single-strand conformational polymorphism), HPA (heteroduplex polymorphism), and CDCE (constant denaturant capillary electrophoresis) and PCR are usually separable using polymer networks. 

Bjorheim J, Lystad S, Lindblom A, et al. Mutation analyses of KRAS exon 1 comparing three different techniques temporal temperature gradient electrophoresis, constant denaturant capillary electrophoresis and allele specific polymerase chain reaction. MutatRes. 1998 403 103-112. 

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