Conjunctival oedema

Mild burning was common in one retrospective review of topical azithromycin for adults with ocular rosacea [109 ]. While one RCT reported no adverse events post keratoplasty [110 ]. Another reported ocular adverse events in 40% contact lens-related dry eye patients, including conjunctival hyperaemia, conjunctival oedema, punctate keratitis, irritation, pain and foreign body sensation [111 ]. 

Tearing, lid er)4hema and oedema, conjunctival hyperaemia and eye closure... 

The conventional test for the irritant and corrosive potential of chemicals is the rabbit eye test, which was developed by Draize et al. (1944), and has become the international standard assay for acute eye irritation and corrosion (EC B.5, Directive 2004/73/EC OECD TG 405, 2002). The test material is applied to the conjunctival sac of the animal s eye and subsequent grading of ocular lesion is established cornea opacity, iris lesion, redness of conjunctivae, and oedema of conjunctivae (chemosis). 

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