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Pectin, amylose, dextran and inulin provide coatings that degrade by enzymes of colonic flora. These polysaccharides are commonly combined with cellulose ethers or esters or synthetic polymers to obtain biphasic release profiles or colon-specific release [29-31]. Drugs conjugated to dextran (linear polymer backbone of a-D-glucopyranose units) show enhanced stability in the upper part of the gastrointestinal tract, but they can be absorbed in the colon [32]. [Pg.330]

See other pages where Conjugate synthetic dextran-enzyme is mentioned: [Pg.129] [Pg.272] [Pg.75] [Pg.539] [Pg.214] [Pg.337] [Pg.520]

See also in sourсe #XX -- [ Pg.129 , Pg.139 ]