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Conformational translesion synthesis

Figure 10.5 (a) Template/primer sequence contexts used for dynamic l9F-NMR and DSC experiments [79]. (b) Example n + 3 translesion synthesis models of BF complexed with AF-modified template/primer DNA n + 3 dC-match (B-type conformer) and n + 3 dA-mismatch (W-conformer) [56]. The carcinogenic aminofluorene moiety is... [Pg.228]

Figure 10.7 Proposed translesion synthesis for Norl-induced -2 deletion mutations. Incorporation of correct dC opposite dG-C8-FAF and subsequent nucleotide incorporation (e.g., dC) can lead to formation of stable S- and B-conformer SMIs (S-SMI and B-SMI, respectively), (a) Sequences for Norl-dC/-2 and Norl-dT/-2 deletion duplexes, (b) The Norl-dC/-2... Figure 10.7 Proposed translesion synthesis for Norl-induced -2 deletion mutations. Incorporation of correct dC opposite dG-C8-FAF and subsequent nucleotide incorporation (e.g., dC) can lead to formation of stable S- and B-conformer SMIs (S-SMI and B-SMI, respectively), (a) Sequences for Norl-dC/-2 and Norl-dT/-2 deletion duplexes, (b) The Norl-dC/-2...
Meneni, S.R., Liang, F., and Cho, B.P. (2007) Examination of the long-range effects of aminofluorene-induced conformational heterogeneity and its relevance to the mechanisms of translesion DNA synthesis. J. Mol. Biol., 366,1387-1400. [Pg.236]

See other pages where Conformational translesion synthesis is mentioned: [Pg.227]    [Pg.361]    [Pg.461]    [Pg.158]    [Pg.197]    [Pg.198]    [Pg.307]    [Pg.167]   
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