Conformation of Polypeptides and

Ramachandran G N and Sasisekharan V 1968 Conformation of polypeptides and proteins Adv. Prof. Chem. 23 283-438... 

Ramachandran, G. N., and V. Sasisekharan. 1968. Conformation Of Polypeptides And Proteins. Adv. Protein Chem. 23, 283M38. 

Pullman, B., and A. Pullman. 1974. Molecular Orbital Calculations on the Conformation of Amino Acid Residues of Proteins, Adv. Protein Chem. 28, 347-526. Ramachandran, G. N., and V. Sasisekharan. 1968. Conformation Of Polypeptides And Proteins, Adv. Protein Chem. 23, 283—438. 

Optical Rotation and the Conformation of Polypeptides and Proteins Peter Urnes and Paul Doty... 

The procedures and calculations described in this chapter provide considerable insight into the factors affecting the conformations of polypeptides and proteins. The computer programs for gramicidin-S, oxytocin, vasopressin, etc., can also be used for larger structures—of the size of ribonuclease and lysozyme—although the required computer time is considerably increased. 

In addition to X-ray diffraction and NMR, which are direct techniques, methods based on the calculation of predicted three-dimensional structures of molecules in the range of 3 to 50 amino acids based on energy considerations are under rapid development. These approaches use what are commonly called molecular dynamics and energy minimization equations to specify the most probable conformation of polypeptides and small proteins. Often, when combined with information from other sources, such as X-ray crystallography or NMR studies, they have been demonstrated to be quite useful. However, when standing alone, their power and the accuracy of their predictive capability remains to be seen. 

Ramachandran GN, Sasisekharan V (1968) Conformation of polypeptides and proteins. Adv Prot Chem 23 283-437... 

Hydrophobic interactions are important in the aggregation of polymethine dyes [81] and in the stabilization of particular conformations of polypeptides and proteins in aqueous solution [222, 232]. They also play an important role in the biochemical com-plexation between an enzyme and a substrate [77, 78, 83, 84, 348]. 

Alemdn, C., Navas, J. J., and Munoz-Guerra, S., Study of the amide - ester hydrogen bond in small molecules and its influence on the conformation of polypeptides and related polymers, J. Phys. Chem. 99, 17653-17661 (1995). 

FANTOM (Fast Newton- http //bose.utmb.edu/fantom/fm Calculation of low-energy conformations of polypeptides and proteins,... 

The random coil and helical conformations of polypeptides and glycopolypeptides were characterized via circular dichroic spectra recorded on a JASCO 810 spectrophotometer (Jasco, Inc., Easton, MD) using a 1-mm path length quartz cuvette in the single-cell mount setup. Background scans of buffer (10 mM phosphate, 150mM NaCl (PBS) pH 7.3) were recorded and automatically subtracted from the sample scans. Samples were made with the... 

G. N. Ramachandran and V. Sasisekharan. Conformation of polypeptides and proteins. Advances in Protein Chemistry, 23 (1968), 283. 

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