Computer-assisted irradiation

Designing Polymers with an Arbitrary Distribution of Characteristic Length Scales by the Computer-Assisted Irradiation (CAI) Method... 

Figure 10.5 The block diagram of the apparatus for the computer-assisted- irradiation method.

Ishino, S., Nakanishi, H., Norisuye, T., Awatsuji, Y. and Tran-Cong-Miyata, Q. (2006) Designing a polymer blend with phase separation tunable by visible light for computer-assisted irradiation experiments. Macromol. Rapid. Commun., 27, 758-762. 

Figure 6.11 Block diagram of the computer-assisted irradiation (CAI) apparatus [55].

Ishino, S. (2006) A novel method of morphology control for polymer alloys using computer-assisted irradiation. Master Dissertation, Department of Polymer Science and Engineering, Kyoto Institute of Technology, Kyoto, Japan, March 2006. 

Figure 6 The SELDI technology. This type of proteomic analytical tool is a class of mass spectroscopy instrument that is useful in high-throughput proteomic fingerprinting of serum. Using a robotic sample dispenser, 1 p,L of serum is applied to the surface of a protein-binding chip. A subset of the proteins in the sample binds to the surface of the chip. The bound proteins are treated with a matrix-assisted laser desorption and ionization matrix and are washed and dried. The chip, which contains multiple patient samples, is inserted into a vacuum chamber where it is irradiated with a laser. The laser desorbs the adherent proteins and causes them to be launched as ions. The TOF of the ion before detection by an electrode is a measure of the mass-to-charge (m/z) value of the ion. The ion spectra can be analyzed by computer-assisted tools that classify a subset of the spectra by characteristic patterns of relative intensity (adapted from www.evmsdoctors.com).

The diazines pyridazine, pyrimidine, pyrazine, and their benzo derivatives cinnoline, phthalazine, quinazoline, quinoxaline, and phenazine once again played a central role in many investigations. Progress was made on the syntheses and reactions of these heterocycles, and their use as intermediates toward broader goals. Some studies relied on solid-phase, microwave irradiation, or metal-assisted synthetic approaches, while others focused attention more on the X-ray, computational, spectroscopic, and natural product and other biological aspects of these heterocycles. Reports with a common flavor have been grouped together whenever possible. 

The photochemistry of a-pyrone (57a) (Scheme 10) was the subject of some of the earliest matrix-isolation studies of organic species. This system still has some interest for further study, however, especially on account of the success that DFT computations have had in assisting with the assignments of matrix IR spectra. Recently, the matrix photolyses of both a-pyrone and its 4,6-di-methyl derivative (57b) have been investigated with the aid of DFT calculations. When (57a) is irradiated (A > 285 nm) in Ar or Kr matrices, rapid formation of rotamers, (58a) and (59a), of the Z isomer of the ring-opened... 

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