Compounds Aldehydes and Ketones

Unsaturated compounds undergo ozonization to initially produce highly unstable primary ozonides (15), ie, 1,2,3-trioxolanes, also known as molozonides, which rapidly spHt into carbonyl compounds (aldehydes and ketones) and 1,3-zwitterion (16) intermediates. The carbonyl compound-zwitterion pair then recombines to produce a thermally stable secondary ozonide (17), also known as a 1,2,4-trioxolane (44,64,125,161,162). 

Much of organic chemistry is simply the chemistry of carbonyl compounds. Aldehydes and ketones, in particular, are intermediates in the synthesis of many pharmaceutical agents, in almost all biological pathways, and in numerous industrial processes, so an understanding of their properties and reactions is essential. We ll look in this chapter at some of their most important reactions. 

The difference in behavior between aldehydes/ketones and carboxylic acic derivatives is a consequence of structure. Carboxylic acid derivatives have ai acyl carbon bonded to a group -Y that can leave as a stable anion. As soon a the tetrahedral intermediate is formed, the leaving group is expelled to general- a new carbonyl compound. Aldehydes and ketones have no such leaving grouj however, and therefore don t undergo substitution. 

In other uses of ge/n-dihalo compounds, aldehydes and ketones add the CH2I group, R2CO —> R2C(OH)CH2l, when treated with CH2I2 in the presence of and the... 

The results of the reaction of carbonyl compounds, aldehydes and ketones, with NH phosphinous amides can be interpreted as occurring on the PH phos-... 

PAHs Heterocyclic nitrogen and oxygen compounds Aldehydes and ketones Sulfides, disulfides ... 

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