Complex Photochemical Biomolecular Switches

36 Biphasic optobioalectronic switch by coupling o DNP-Ab with a dlnitrospiropyran-funcdonalized GOx monolayer electrode. 

EUGENII KATZ.ANDREW N. SHIPWAY,AND ITAMAR WILLNER 

Substantial progress has been accomplished in the fabrication of molecular and biomolecular optoelectronic devices. Light-activated molecular and bio-molecular systems have been integrated with electronic transducers, and the optical switching of the systems has been electronically transduced to the macroscopic environment. In particular, the photonic switching of an electron-transfer cascade has allowed the amplified electronic transduction of an input 

38 (A) The assembly and photnisomerization of a switchabie rotaxane on aAu-eleomode. (B) The chronoamperometric response of the monolayer in (a) the trans-estate, and (b) the ds-state. (C) The electron transfer rate constant between the ele xrode and the ferrocene component (28) over four photoisomerization cycles. Electrochemistry was performed in 0.1 M phosphate buffer (pH 7.3). 

36 Biphasic optobloelectranic switch by couf ing of DNP-Ab with a dinitrospiropyran-functionalized GOx monolayer electrode. 

6 INTERLOCKED COMPOUNDSAS MECHANICAL COMPONENTS AT PHOTOISOMERIZABLE INTERFACES 

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