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Comparative structural genomics

Structural Genomics, Functional Genomics, and Comparative Genomics... [Pg.54]

Fleming, R, Muller, A, MacCallum, R M., Sternberg, M. J. (2004). 3D-GENOMICS A database to compare structural and functional annotations of proteins between sequenced genomes. Nucleic... [Pg.563]

The simnlation and modeling of protein structures assists in refining the structural determinations and speeds up the sftucture analysis, especially when using comparative modeling, based on the fact that protein families share similar architectures and sequences. " Table 1.7 fists websites related to the use of NMR in structural genomics. [Pg.69]

The functions of a large proportion of the proteins encoded by the human genome are presently unknown. Recent advances in bioinformatics permit researchers to compare amino acid sequences to discover clues to potential properties, physiologic roles, and mechanisms of action of proteins. Algorithms exploit the tendency of nature to employ variations of a structural theme to perform similar functions in several proteins (eg, the Rossmarm nucleotide binding fold to bind NAD(P)H,... [Pg.28]

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See also in sourсe #XX -- [ Pg.430 ]



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Comparative genomic

Genome comparative

Structural genomics

Structure comparative

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