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Combinatorial synthesis cation flow” method

Serial Combinatorial Synthesis Based on the Cation Flow Method... [Pg.212]

An outstanding feature of the cation flow method is that the method enables continuous sequential combinatorial synthesis by simple flow switching as shown in Figure 6. In the first step, the cation flow generated from precursor A1 is allowed to react with nucleophile Bl. Then, the cation flow is allowed to react with the nucleophile B2. In the third step, the cation flow is allowed to react with nucleophile B3. Then, the precursor of the cation is switched to A2, and the cation flow generated from A2 is allowed to react with nucleophiles Bl, B2, and B3 sequentially. Then, the precursor of the cation is switched to A3, and the... [Pg.212]

Figure 4.3 Serial combinatorial synthesis based on the cation flow method. (a) Schematic diagram (b) example based on the reaction of N-acyliminium ion pools with carbon nucleophiles... Figure 4.3 Serial combinatorial synthesis based on the cation flow method. (a) Schematic diagram (b) example based on the reaction of N-acyliminium ion pools with carbon nucleophiles...
J. Yoshida, S. Suga, Basic concepts of cation pool and cation flow methods and their applications in conventional and combinatorial organic synthesis, Chem. Eur. J. 2002, 8, 2650-2658. [Pg.592]

Figure 9.7 Serial combinatorial synthesis based on the cation flow method. Figure 9.7 Serial combinatorial synthesis based on the cation flow method.
See other pages where Combinatorial synthesis cation flow” method is mentioned: [Pg.379]    [Pg.229]    [Pg.252]   
See also in sourсe #XX -- [ Pg.199 ]

See also in sourсe #XX -- [ Pg.199 ]



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