Combinatorial library electrochemical characterization

Black, M., Cooper, J., McGinn, P. Scanning electrochemical microscope characterization of thin film combinatorial libraries for fuel cell electrode applications. Meas. Sci. Technol. 2005, 16, 174—182. 

Fig. 11.8 Schematic of the automated primary high-throughput electrochemical workflow employed at Symyx Technologies for the combinatorial development of new fuel cell catalysts. Individual steps of the workflow include choice of catalyst concept, design of appropriate materials library using Library Studio [31], synthesis of electrocatalyst library on electrode array wafer, XRD and EDX characterization of individual electrocatalysts before screening, high-throughput parallel electrochemical screening of library, XRD and EDX characterization of catalysts after screening, data processing and evaluation.

The electrochemical robotic system was first applied for characterization of a combinatorial substance library.67 256 quarter (3-arylthiophenes) were screened by means of cyclic voltammetry to reveal their redox properties. The first oxidation potentials leading to the formation of the radical cation of the investigated species could be correlated with the electronic effects of the individual substituents (Fig. 14.18). 

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