Collision-induced dissociation cationization mass spectrometry

Afonso, C. Riu, A. Xu, Y. Fournier, R Tabet, J.-C. Structural characterization of fatty acids cationized with copper by electrospray ionization mass spectrometry under low-energy collision-induced dissociation. J. Mass Spectrom. 2005, 40, 342-349. 

Metal-ethoxo cations derived from solutions of B(C6F5)3 and M2(OEt)10 were observed in the gas phase by electrospray mass spectrometry.293 They included [M(OEt)4]+, [M2(OEt)9]+, and [M20(0Et)7]+ as well as heterometallic analogs when both metals were present in the sprayed solutions. Their fragmentation behavior under collision-induced dissociation was examined. 

Properties of the complexes of alkali metal cations with various bases are important in understanding ion-molecule interactions, solvation effects, biomedical and physiological phenomena related to ion channels and relevant in medical treatments. Reliable experimental bond dissociation enthalpies, and thereby gas-phase alkali ion affinities, could now be obtained using various mass spectrometry techniques such as the Fourier-transform ion cyclotron resonance (FT-ICR), collision-induced dissociation and photodissociation methods. However, these methods do not provide direct information on the adduct structures. 

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