Collagens network-forming

Network-forming collagens (types IV, VIII, andX)... 

In fat tissues, capillaries and collagen fibers form a supporting network around spherical adipocytes. Almost the entire volume of these metabolically active cells is taken up by fat droplets. 

Network-forming collagens Types IV and VII form a three-dimensional mesh, rather than distinct fibrils (Figure 4.4). For example, type IV molecules assemble into a sheet or meshwork that constitutes a major part of basement membranes. [Note Basement membranes are thin, sheet-like structures that provide mechanical support for adjacent cells, and function as a semipermeable filtration barrier for macromolecules in organs such as the kidney and the lung.]... 

Electron micrograph of a polygonal network formed by association of collagen type IV monomers. 

IV. Common Structural Themes in Network-Forming Collagens. 396... 

This Chapter contains a description of the main network-forming collagens. It highlights the main structural characteristics of each individual collagen that allow network formation, and ends by discussing the underlying structural commonalities between different network collagen types. 

II. Network-Forming Collagens in Detail A. Type TV Collagen... 

Knupp, C., and Squire, I. M. (2003). Molecular packing in network-forming collagens. Sd. World J. 3, 558-577. 

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