Triple helix, collagen structure

Brodsky, B. and Ramshaw, J.A.M. (1997) The collagen triple-helix structure. Matrix Biology, 15, 545-549. 

Computational studies starting with collagen triple-helix structures now available in the Protein Data Bank are becoming increasingly important for collagen. As described above, molecular dynamics simulations can suggest models that are amenable to experimental verification. Computational analyses and molecular dynamics studies have also been carried out on Gly substitutions in the triple helix (see Section VIII below). 

Berisio, R., Vitagliano, L., Mazzarella, L., and Zagari, A. (2002). Recent progress on collagen triple helix structure, stability and assembly. Prot. Pept. Lett. 9, 107-116. 

Where is the collagen triple helix structure not found ... 

Engel J, Bachinger H-P (2005) Structure, Stability and Folding of the Collagen Triple Helix. 247 7-33... 

COLLAGEN TYPE I IS COMPOSED OF A TRIPLE HELIX STRUCTURE FORMS FIBRILS... 

Atomic Structures of the Collagen Triple Helix and Collagen Trimerization Domains 510... 

Figure 16 Interchain hydrogen bond network in collagen triple helix. The figure was generated using the UCSF Chimera package and coordinates from PDB structure 1QSU.

The availability of high-resolution structures of peptides EKG, T3-785, IBP, and G991-G1032, which include residues other than Pro and Hyp in the X and Y positions, offers the opportunity to investigate the conformation and interactions of side chains from residues typically found within the collagen triple helix. In the peptide with an EKG tripeptide sequence, the Lys and Glu residues did not form direct intermolecular or intramolecular ion pairs, even though such pairs are sterically feasible. ... 

Despite the requirement ofNC domains for correct oligomerization of the collagen triple helix, the NC domain structures are divergent among all collagens. The structure of the NCI domain of type IV collagen " is... 

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