Collagen fibrillogenesis

Work by Haston et al. (2002) also indicates that acidic glycoprotein (AGP) influences Type II collagen fibrillogenesis, where in vitro studies show that low concentrations of AGP produced decreases in fibrillogenesis rate and fibril diameter. High concentrations produced fibrils at a rate and diameter dependent on fucosylation of AGP. Highly fucosylated AGP produced narrow fibrils, and poorly fucosylated AGP produced thicker fibrils. 

Collagen fibrillogenesis in situ Fibril segments become long fibrils as the developing tendon matures. Dev. Dynam. 208, 291-298. 

Otter, A., Scott, P. G., and Kotovych, G. (1988). Type-I collagen a-lchain C-telopep-tide—Solution structure determined by 600 MHz proton NMR spectroscopy and implications for its role in collagen fibrillogenesis. Biochemistry 27, 3560-3567. 

Parkinson, J., Kadler, K. E., and Brass, A. (1995). Simple physical model of collagen fibrillogenesis based on diffusion-limited aggregation./. Mol. Biol. 247, 823-831. 

Birk DE, Silver FH. Collagen fibrillogenesis in vitro Comparison of types I, II and III, Arch Biochem Biophys. 1984 235 178-185. 

Ingman WV, Wyckoff J, Gouon-Evans V, CondeeUs J, Pollard JW (2006) Macrophages promote collagen fibrillogenesi.s around terminal end buds of the developing mammary gland. Dev Dyn 235 3222-3229... 

Hedbom E, Heinegard D. Interaction of a 59-kDa connective tissue matrix protein with collagen I and collagen II. J Biol Chem 1989 264 6898-6905. Neame PJ, Kay CJ, McQuillan DJ, Beales MP, Hassell JR. Independent modulation of collagen fibrillogenesis by decorin and lumican. Cell Mol Life Sci 2000 57 859-863. 

Farber, S., Garg, A. and Silver, EH. (1986) Collagen fibrillogenesis in vitro Evidence of preiiucleation and nucleation steps. Int. J. Biol. Macromol, 8, 37-42. 

Silver, RIT., Langely, K.H. and Trelstad, R.L. (1979) Tfpe I collagen fibrillogenesis Initiation ria reversible linear and lateral growth steps. Biopolymers, 18, 252.3-2535. 

K.E. Kadler, A. Hill, and E.G. Canty-Laird, Collagen fibrillogenesis Eibronectin, integrins, and minor collagens as organizers and nucleators, Curr. Opin. Cell Biol, 20 (5), 495-501,2008. 

Fig. 6 Turbidity measurements of collagen fibrillogenesis in the presence of heparin and hyaluronic acid 2 h after initiation of fibril formation. Initial concentration of the non-fibrUlar collagen solution was 1.2 mg/ml. Concentrations of the glycosaminoglycans were 0.4, 1.2, and 4.0 mg/ml, respectively...

Rada, J.A., P.K. Comuet, and J.R. Hassell. 1993. Regulation of corneal collagen fibrillogenesis in vitro by comeal proteoglycan (lumican and decorin) core proteins. Exp. Eye Res. 56 635-648. 

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