Collagen-based Structures Containing Peptoid Residues

Collagen-based Structures Containing Peptoid Residues 

Collagen is the major protein component of coimective tissue and constitutes approximately 25% of the total protein content in humans. There are more than 19 

The ability of these peptidomimetic collagen-structures to adopt triple helices portends the development of highly stable biocompatible materials with collagenlike properties. For instance, it has been found that surface-immobilized (Gly-Pro-Meu)io-Gly-Pro-NH2 in its triple-helix conformation stimulated attachment and growth of epithelial cells and fibroblasts in vitro [77]. As a result, one can easily foresee future implementations of biostable collagen mimics such as these, in tissue engineering and for the fabrication of biomedical devices. 

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Collagen-based Structures Containing Peptoid Residues... 

M. Collagen-based structures containing the peptoid residue N-isobutylglycine (3t(leu) Synthesis and biophysical studies of Gly-Nleu-Pro sequences by circular di-chroism. Biochemistry 1997, 36, 8716-8724. 

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