Cohesion parameter

A. F. M. Martin, Handbook of Solubility Parameters and Other Cohesion Parameters, CRC Press, Inc., Boca Raton, Fla., 1983. 

Large databases for the solubility parameter exist, most notably Barton s Handbook of Solubility Parameters and Other Cohesive Parameters [112], A small listing of values is given in Table 4. The units used are those of (J/cm ) / = (MPa) /, although the older literature uses units of (cal/cm ). The units are related by ... 

Solvent selection based on cohesion parameters, like those of Hansen [12], and by multivariate statistical methods like principal components analysis are two potential methods that can be used for solvent selection. These effects will be examined further in section 3.6.1. 

Barton, A M F Handbook of Solubility Parameters and Other Cohesive Parameters, CRC Press Boca Raton, 1983... 

Barton AFM (1991) ORC handbook of solubility parameters and other cohesion parameters, 2nd edn. CRC Press Inc, Boca Raton FL... 

Maitani, Y., A. Coutel-Egros, Y. Obata, and T. Nagai. 1993. Prediction of skin permeabilities of diclofenac and propranolol from theoretical partition coefficients determined from cohesion parameters. ]. Pharm. Sci. 82(4) 416-420. 

In this table, we provide solubility parameters for some liquid solvents that can be used as modifiers in supercritical fluid extraction and chromatography. The solubility parameters (in MPa1/2) were obtained from reference 3, and those in cal1/2cm 3/2 were obtained by application of Equation 4.1 for consistency. It should be noted that other tabulations exist in which these values are slightly different, since they were calculated from different measured data or models. Therefore, the reader is cautioned that these numbers are for trend analysis and separation design only. For other applications of cohesive parameter calculations, it may be more advisable to consult a specific compilation. This table should be used along with the table on modifier decomposition, since many of these liquids show chemical instability, especially in contact with active surfaces. 

Barton AFM, "Handbook of Solubility Parameters and other Cohesion Parameters ", CRC Press. Boca Raton, FL, 2nd Ed, 1991... 

Barton AFM (1983) Handbook of solubility parameters and other cohesive parameters, CRC, Boca Raton, FL... 

Because the term solubility parameter is too restrictive for this quantity, which can be used to correlate a wide range of physical an chemical properties (for instance, cf. Section 5.4.2), the term cohesion parameter has been proposed by Barton [99]. The term solubility parameter suggests a close relationship between the phenomenon solubihty or miscibility and that of cohesion or vapourization . This seems to be reasonable, considering what happens in a mixing process the like molecules of each component in a mixture are separated from one another to an infinite distance, comparable to what happens in the vapourization process. A comprehensive review on the determination and application of solubility parameters has been given by Barton [99],... 

Aprotic Solvents, in J. F. Coetzee and C. D. Ritchie (eds.) Solute-Solvent Interactions, Dekker, New York, London, 1969, Vol. 1, p. 219ff. [95] H. Liebig Prdparative Chemie in aprotonischen Ldsungsmitteln, Chemiker-Ztg. 95, 301 (1971). [96] E. S. Amis and J. F. Hinton Solvent Effects on Chemical Phenomena, Academic Press, New York, London, 1973, Vol. 1, p. 271ff. [97] P. K. Kadaba Role of Protic and Dipolar Aprotic Solvents in Heterocyclic Syntheses via 1,3-Dipolar Cycloaddition Reactions, Synthesis 1973, 71. [98] J. H. Hildebrand and R. L. Scott The Solubility of Nonelectrolytes, 3 ed., Reinhold, New York, 1950 Dover, New York, 1964 J. H. Hildebrand and R. L. Scott Regular Solutions, Prentice-Hall, Englewood Cliffs/New Jersey, 1962 J. H. Hildebrand, J. M. Prausnitz, and R. L. Scott Regular and Related Solutions, Van Nostrand-Reinhold, Princeton/New Jersey, 1970. [99] A. E. M. Barton Handbook of Solubility Parameters and other Cohesion Parameters, CRC Press, Boca Raton/Elorida, 1983. [100] M. R. J. Dack, Aust. J. Chem. 28, 1643 (1975). 

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