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Clopidogrel Plavix Enzymatic Preparation of 2-Chloromandelic Acid Esters

Anticancer drugs enzymatic synthesis of taxane side chain. [Pg.85]

18 ANTIDIABETIC AND CNS DRUGS ENZYMATIC HYDROLYSIS OF DIMETHYL BICYCLO[2.2.1]HEPTANE-1,4-DICARBOXYLATE [Pg.85]

19 CLOPIDOGREL (PLAVIX) ENZYMATIC PREPARATION OF 2-CHLOROMANDELIC ACID ESTERS [Pg.85]

An efficient process for resolving methyl 2-chloromandelate (l ,S)-64 was developed using a lipase-mediated transesterification. Among 11 hydrolytic enzymes examined, C. antarctica lipase A (CAL-A) showed the highest enantioselectivity and [Pg.85]

Antidiabetic and CNS drugs enzymatic hydroiysis of dimethyi bicycio[2.2.1]heptane-1, 4-dicarboxyiate. [Pg.86]


Clopidogrel (Plavix) enzymatic preparation of 2-chloromandelic acid esters. [Pg.86]




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2-Chloromandelic acid esters

2-chloromandelic acid

Chloromandelates

Clopidogrel

Clopidogrel (Plavix

Enzymatic preparation, 2-chloromandelic

Enzymatic preparation, 2-chloromandelic acid esters

Esters preparation

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