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Clinical studies, neutralizing antibody assays

Finally, it should be mentioned that for both the animal studies and the clinical studies in humans, serological assays have to be developed in advance. These tests are required for the detection of the protein drug in serum or plasma (pharmacokinetic) as well as for the detection of specific antibodies evoked by the drug. If antibodies appeared, they have to be further analyzed for neutralizing activity. This could be demonstrated by an inhibitory effect in the bioassay. [Pg.142]

See other pages where Clinical studies, neutralizing antibody assays is mentioned: [Pg.194]    [Pg.196]    [Pg.223]    [Pg.2015]    [Pg.117]    [Pg.67]    [Pg.1570]    [Pg.1835]    [Pg.195]    [Pg.195]    [Pg.222]    [Pg.224]    [Pg.225]    [Pg.366]   
See also in sourсe #XX -- [ Pg.223 , Pg.224 ]



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Clinical antibodies

Neutralizing assays

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