Clark, Alfred

Cheng-Prasoff relationship, 65-66, 214 Cholecystokinin receptor antagonists, 80 Cimetidine, 9-10 Clark, Alfred J., 3, 3f, 12, 41 Clark plot, 114 Clearance, 165—166 Clinical pharmacokinetics, 165 Cocaine, 149, 150f Competitive antagonism description of, 114 Gaddum equation for, 101-102, 113,... 

Clark, Alfred, The Theory of Adsorption and Catalysis, Academic Press, 1970. 

Carol J. Burns, David L. Clark Alfred P. Sattelberger... 

SUBMITTED BY DAVID L. CLARK and ALFRED P. SATTELBERGER CHECKED BY RICHARD A. ANDERSEN ... 

Ronald W. Clark, The Life of Bertrand Russell (New York Alfred A. Knopf, 1976), p. 457. 

No less revolutionary in the quantification of pharmacodynamics was the insistance on size relationships which Alfred Joseph Clark (London) introduced in his book, The Mode of Action of Drugs on Cells (Clark, 1933). The mnemonic diagram that forms the frontispiece of the present book will serve to introduce this aspect. In it we see a typical mammal (dog) followed by a typical insect (flea) which is a thousand times smaller, and this is followed by a typical microbe (streptococcus) which is yet a thousand times smaller, and finally a typical bioactive molecule (p-aminobenzoic acid) which is one thousand times smaller still. Thus we have familiar reference objects staked out over a size-range of 10 (a million-millionfold). 

D.W. Hill, Cooperative research in industry (London, 1946) Ronald S. Edwards, Cooperative Industrial Research. A study of the economic aspects of the research assocications (London, 1949) Alfred D. Chandler Jr., "From industrial laboratories to departments of research and development," in Kim B. Clark, Robert H. Hayes, and Christopher Lorenz, eds.. The uneasy alliance. Managing the productivity-technology dilemma (Boston, 1985), 53-61 Edgerton and Horrocks (ref. 1). 

Lohr, Wlnrich Alfred. Gnostic Determinism Reconsidered. VC 46 (1982) 381-390. Logan, Alastalr. The Gnostics Identifying an Earty Christian Cult. London T. T. Clark, 2006. 

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