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Cis-SNARE-complex

Acceptor complex Monomeric/dustered-SNAREs Cis-SNARE-complexes... [Pg.112]

Fig. 2 The conformational cycle of SNAREs. SNAREs cycle between two extreme conformations, the unstructured monomeric SNAREs and the fully assembled cis-SNARE complexes. Initially, SNAREs on the membranes destined to fuse establish trans-SNARE complexes between the opposed membranes. Proceeding SNARE complex assembly forces the membranes tightly together enforcing membrane fusion. The resulting cis-SNARE complexes are disassembled into free SNAREs by the ATPase NSF and its co-factor, a process that consumes ATP and fuels the SNAREs with energy for undergoing a new SNARE cycle (for details see text). Fig. 2 The conformational cycle of SNAREs. SNAREs cycle between two extreme conformations, the unstructured monomeric SNAREs and the fully assembled cis-SNARE complexes. Initially, SNAREs on the membranes destined to fuse establish trans-SNARE complexes between the opposed membranes. Proceeding SNARE complex assembly forces the membranes tightly together enforcing membrane fusion. The resulting cis-SNARE complexes are disassembled into free SNAREs by the ATPase NSF and its co-factor, a process that consumes ATP and fuels the SNAREs with energy for undergoing a new SNARE cycle (for details see text).
See other pages where Cis-SNARE-complex is mentioned: [Pg.108]    [Pg.112]    [Pg.115]    [Pg.230]    [Pg.108]    [Pg.112]    [Pg.115]    [Pg.230]    [Pg.150]   
See also in sourсe #XX -- [ Pg.112 ]



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