Ciprofloxacin in children

Children Tobramycin is safe and effective in children. Safety and efficacy of ciprofloxacin in children younger than 12 years of age and norfloxacin and ofloxacin in infants younger than 1 year of age have not been established. 

Data on more than 1500 children treated with ciprofloxacin suggest that the safety profile of ciprofloxacin in children and adolescents is similar to the profile in adults (57). Adverse events, mostly involving the gastrointestinal tract, were noted in 5-15% of patients. Reversible... 

In a comparison of intravenous and oral ciprofloxacin in children, treatment associated adverse events were reported in 11% of children taking oral ciprofloxacin, compared with 19% of the children who were treated intravenously (68). In 31 children (1.5%) arthralgia occurred, but it was generally mild to moderate and resolved spontaneously. 

Singh UK, Sinha RK, Prasad B, Chakrabarti B, Sharma SK. Ciprofloxacin in children is arthropathy a limitation Indian J Pediatr 2000 67(5) 386-7. 

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