Chronic disease clinical presentation

Many clinical studies have been performed on human subjects to assess the effect of soy isoflavones on chronic disease risk factors with no ill-effects (see Section 10.4). The safety profile of isoflavones is, however, difficult to establish because of the limited sample sizes and short periods of investigation of such studies. At present the upper tested limits are ... 

Clinical Presentation of Chronic Obstructive Pulmonary Disease... 

The clinical presentation for IE is quite variable and often nonspecific. A fever is the most frequent and persistent symptom in patients but may be blunted with previous antibiotic use, congestive hear failure, chronic liver or renal failure, or infection caused by a less virulent organism (i.e., subacute disease).3 Other signs and symptoms that also may occur are listed in the Clinical Presentation box with some discussed further in detail below. 

Lecamwasam, D., Synek, B., Moyles, K., Ghose, K. (1994). Chronic lithium neurotoxicity presenting as Parkinson s disease. International Clinical Psychopharmacology, 8, 127-129. 

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