Chromatographic Resolution of Optically Active Compounds

Derivatization for Chromatographic Resolution of Optically Active Compounds 

Residue and Environmental Chemistry, ICI Agrochemicals, Jealotts Hill Research Station, Bracknell, Berkshire 

SELECTION OF CHIRAL DERIVATIZING REAGENTS FOR CHROMATOGRAPHIC RESOLUTION OF ENANTIOMERS 

Optically active compounds form an integral part of all biological systems and are almost exclusively found in a single enantiomeric form. These systems therefore constitute a chiral environment in which the enantiomers of chiral xenobiotics may exhibit very different properties and behave as two totally different entities typical examples of the different responses are shown in Table 1. 

Edited by K. Blau and J. M. Halket 1993 John Wiley Sons Ltd 

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