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Chromatin psoralen probing

Psoralen-Probing of Chromatin Organization in Intact Cells... [Pg.231]

G. Mathis and F.R. Althaus Psoralen-Probing of Chromatin Organization in Intact Cells... [Pg.234]

Psoralen derivatives offer a number of distinct advantages as chemical probes for chromatin structure in intact cells [1-5, 9] (1) Psoralens are readily taken up by intact cells (2) a number of psoralens have been shown to intercalate specifically into free DNA. Upon activation by UV 365 nm, intercalated psoralens form stable monoadducts and some derivatives give rise to interstrand cross-links. These cross-hnks can be visualized by electron microscopy [1]. [Pg.230]

Sogo JM, Ness PJ, Widmer RM, Parish RW, Koller T (1984) Psoralen crosslinking of DNA as a probe for the structure of the active nucleolar chromatin. J Mol Biol 178 897-928... [Pg.233]

Mathis G, Althaus FR (1985) Probing chromatin organization with psoralens Alterations during DNA excision repair. This volume... [Pg.242]

See other pages where Chromatin psoralen probing is mentioned: [Pg.233]    [Pg.236]   
See also in sourсe #XX -- [ Pg.230 , Pg.231 , Pg.232 , Pg.233 , Pg.234 , Pg.235 , Pg.236 , Pg.237 , Pg.238 , Pg.239 , Pg.240 ]



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