Chromatin overview

So far nine arginine methyltransferases [46] and more than 20 lysine methyltransferases [11] have been identified in humans. Many of them show links to cancer. We discuss several of these subtypes below and an overview can be found in Tables 12.1 and 12.2. For lysine methyltransferases traditionally individual names have been used for the various subtypes. Lately, a common nomenclature for chromatin modifying enzymes has been proposed. For the human lysine methyltransferases the name KMTs should be used in analogy to (P)RMTs and eight groups (KMTl-8) with different subtypes suggested for some members [47]. But this nomenclature is not used consistently even throughout the recent literature so we provide both names if available in Table 12.2. 

A. The Miller Chromatin Spreading Method Overview and Brief History... 

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