Chondrus ocellatus

C. Araki and S. Hirase, Partial methanolysis of the mucilage of Chondrus ocellatus Holmes, Bull. Chem. Soc. Jpn., 29 (1956) 770-775. 

G. Zhou, Y. Sun, H. Xin, Z. Zhang, and Z. Xu, In vivo antitumor and immunomodulation activities of different molecular weight lambda-carrageenans from Chondrus ocellatus, Pharm. Res., 50 (2004) 47-53. 

Zhou, G., Sheng, W., Yao, W. Wang, C. (2006) Effect of low molecular A-carrageenan from Chondrus ocellatus on antitumor H-22 activity of 5-Fu. Pharmacol. Res. 53.129-134. 

These findings led to the preparation of k-carrageenans of low molar mass (9.3, 15, 140, 240, and 650 kDa) by microwave degradation of the carrageenan of Chondrus ocellatus. These degraded k-carrageenans have immimos-timulant properties and have been shown to enhance the antitumor activity of 5-fluorouradl (5-FU) in mice transplanted with SIO and H-22 tumors (Yamada et al., 1997 Zhou et al., 2004, 2005, 2006). 

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