Chondrogenic markers

Equine Monolayer, fibrin disks 0.5 ng/mL TGF-Pl monolayer 6 days. 0. 100 ng/mL IGF-1 fibrin disks 13 days Monolayer with TGF-Pl increased proliferation, disks with both growth factor treatments increased gene and protein expression for chondrogenic markers over controls... 

Human Monolayer or pellet. 5% Oj or 20% Oj ITS. dexamethasone, 10 ng/mL TGF-(il 28 days Histology, gene and protein expression all chondrogenic markers upregulated in 5% Oj... 

Human Alginate ITS, dexamethasone, 10 ng/mL TGF-Pl, 10 ng/mL TGF-P3, 100 ng/mL IGF-1, 500 ng/mL BMP 6 7 days Gene and protein expression indicate BMP 6 alone significantly more efficient at upregulating chondrogenic markers than all other growth factors/combinations... 

Goat bone marrow stromal cells Perfusion 0.1 ml/ min, static Starch-PCL fiber mesh ITS. FBS. dexamethasone. 10 ng/mL pi 28 days Bioreactor groups significantly higher protein and gene expression for chondrogenic markers compared to static controls... 

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