Choline headgroup

Although the stabilizing interactions between the amino acid side chains of PLC/j, and the choline headgroup are readily apparent in the PLC fc-phosphonate inhibitor complex, it is more difficult to identify contacts between the protein and the acyl chains of the inhibitor [45]. In part this is because thermal motion in the acyl side chains, especially the sn-1 chain, renders them somewhat disordered. Consequently, the measured distances between the side chain carbons... 

Morrow et al. also examined the effects of pressure and temperature on DPPC and DMPC choline headgroup conformation using deuterium nuclear magnetic resonance. The electric dipole resulting from charge separation in... 

The Klymchenko group introduced a hierarchical assembly protocol between amphiphilic calixarenes such as 71 and DNA to generate virus-sized nanoparticles for gene delivery (Fig. 24.24). In a two-step process cationic calix[4]arenes with choline headgroups at the upper and long alkyl tails at the lower rim were subjected... 

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