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Cholecystokinin, discovery

Evans BE, Rittle KE, Bock MG, et al. (1988) Methods for drug discovery Development of potent, selective, orally effective cholecystokinin antagonists. /. Med. Chem. 31 2235-2246. [Pg.34]

Cholecystokinin (CCK) is one of a number of peptides that act both as gut hormones and neurotransmitters in the central nervous system (CNS). Through the discovery of selective agonists and antagonists it has been possible to show that CCK acts through at least two receptor subtypes, CCK-A and CCK-B. The former are found mainly in the periphery, whilst the latter are located extensively in the CNS. [Pg.375]


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See also in sourсe #XX -- [ Pg.115 ]




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Cholecystokinin

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