Chloroacetylhydrazide hydrochloride

Chloroacetylhydrazide hydrochloride, ClCHjCONHNHj-HCl. Mol. wt. 145.00, m.p. 150° dec. The reagent is prepared by reaction of the activated p-nitrophenyl ester (1) with hydrazine. It is used for the generation of diimide, which see. 

According to a preliminary report, diimide can be generated at 0° by the action of sodium hydroxide on chloroacetylhydrazide hydrochloride (which see). Another precursor is hydroxylamine-O-sulfonic acid (which see). Azobenzene has been reduced quantitatively to hydrazobenzene and tdlyl alcohol to propanol (70%). ClCHjCONHNHi HCl + 2 NaOH ----------> CH2=C=0 + HjO + HN=NH + 2 NaCff... 

Diimide precursors Chloroacetylhydrazide hydrochloride. Hydrazine. Hydroxylamine-O-sulfonic acid. Potassium azodicarboxylate. o-Diketone adduct Triethyl phosphite. 

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See also in sourсe #XX -- [ , ]

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