6- Chloro-2-pyrazinecarboxamide 4-oxide

Chloro-2-pyrazinecarboxamide 4-oxide (11) gave 6-chloro-2-pyrazinecar-boxylic acid 4-oxide (12) (NaNOz, 50% H2S04, 20°C, 1 h, then 60°C, 1 h 75% presumably this indirect method was adopted to avoid hydrolysis of the chloro substituent).669... 

Chloro-2-pyrazinecarboxamide 4-oxide 6-Chloro-2-pyrazinecarboxamidrazone 3-Chloro-2-pyrazinecarboxylic acid... 

Chloro-2-pyrazinecarboxamide 4-oxide (11) gave 6-chloro-2-pyrazinecar-... 

Chloro-5,6-diphenyl-2-pyrazinecarbohydrazide 5-Chloro-3,6-diphenyl-2-pyrazinecarbonitrile 3-Chloro-5,6-diphenyl-2-pyrazinecarboxamide 2-Chloro-3,5-diphenylpyrazine 1 -oxide 2-Chloro-3,6-diphenylpyrazine 1-oxide 2-Chloro-3,6-diphenylpyrazine 4-oxide 2-Chloro-5,6-diphenylpyrazine 1-oxide... 

Chloro-5-isobutylpyrazine 6-Chloro-5-isobutyl-2-pyrazinecarbothioamide 6-Chloro-5-isobutyl-2-pyrazinecarboxamide 2-Chloro-3-isobutylpyrazine 4-oxide 2-Chloro-5-isopentyl-3,6-dimethylpyrazine 2-Chloro-3-isopropenyl-6-isopropyl-5-methoxypyrazine 5-Chloro-6-isopropenyl-3-isopropyl-l-methyl-2(177)-pyrazinone... 

Ethyl 3-amino- l-benzyl-5-isobutyl-6-oxo-1,6-dihydro-2-pyrazinecarboxylate 4-oxide Ethyl 3-amino-6-benzyloxy-5-isobutyl-2-pyrazinecarboxylate 4-oxide Ethyl 3-amino-6-chloro-5-ethoxy-2-pyrazinecarboxylate Ethyl 6-amino-3-chloromethyl-5-cyano-2-pyrazinecarboxylate Ethyl 6-amino-3-chloromethyl-5-cyano-2-pyrazinecarboxylate 1-oxide Ethyl 3-amino-5-chloro-6-methyl-2-pyrazinecarboxylate Ethyl 3-amino-5-chloro-6-phenyl-2-pyrazinecarboxylate Ethyl 5-amino-6-cyano-3-methyl-2-pyrazinecarboxylate Ethyl 6-amino-5-cyano-3-methyl-2-pyrazinecarboxylate Ethyl 6-amino-5-cyano-3-methyl-2-pyrazinecarboxylate 1-oxide Ethyl 3-amino-5,6-dimethyl-2-pyrazinecarboxylate 5-Ethylamino-6-ethylcarbamoyl-3-methylami no-2-pyrazinecarboxamide... 

---