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5-Chloro-2-pyrazinamine

Chloro-2-pyrazinamine (121, R = Cl) gave 3-benzyloxy-2-pyrazinamine (121, R = OCH2Ph) (PhCH2ONa, PhCH2OH, warmed , 72 h 58% sometimes accompanied by a separable byproduct, 2-benzylamino-3-benzy-loxypyrazine (122), in small amount.1567, cf-616... [Pg.161]

Chloro-2-pyrazinecarboxamide (73) gave 3-chloro-2-pyrazinamine (74) [NaOBr (made in situ), H20, 80°C, 2 h 83%).1681... [Pg.271]

Bromo-5-chloro-6-phenyl-2(177)-pyrazinone 3-Bromo-5-chloro-2-pyrazinamine 5-Bromo-3-chloro-2-pyrazinamine 5-Bromo-3-chloro-2(177)-pyrazinone... [Pg.377]

Dichloro-3-nitro-2-pyrazinamine and ethyl 3-aminocrotonate gave 5-(2-amino-1 -ethoxycarbonylprop-1 -enyl)-6-chloro-3-nitro-2-pyrazinamine (107) (Et3N, Pr OH, 20°C, 16 h 62%).788... [Pg.95]

Pyrazinamine gave 5-chloro-2-pyrazinamine (27) [substrate, CHC13—pyridine, Cl2(1.2 mol)/CHCl3 [ slowly, 20°C, dark, 3 h 26% after purification].1280... [Pg.142]

The conversion of (primary) pyrazinamines into the corresponding halogenopyrazines by one-pot diazotization and treatment with halides has proven reasonably satisfactory for making some chloro-, bromo-, or fluoropyrazines to date, iodopyrazines... [Pg.146]

There is little recent information in this area. The tine structure of 3-acetoxy-l, 4-dinitro-2-piperazinol (14) has been elucidated by X-ray analysis.1212 Treatment of 5,6-dichloro-3-nitro-2-pyrazinamine (15) with refluxing ethanolic sodium cyanide for 4 days induced displacement of the nitro by a cyano group as well as ethanoly-sis of one chloro substituent to afford 3-amino-6-chloro-5-ethoxy-2-pyrazinecar-bonitrile (16) in 55% yield.1313 L-Methyl-4-(/>nitrobenzoyl)pipcrazine (17) gave I -(/ -aminobenzoyl)-4-methy I piperazine (18) (75%) on refluxing in ethanolic hydrazine hydrate with a little Raney nickel catalyst for 6 h 135, cf 1032 other reduction procedures have been reported.496,1741... [Pg.261]

Chloro-2-pyrazinecarbonyl chloride (126) and 2-pyrazinamine gave 6-chloro-Ar-(pyrazin-2-yl)-2-pyrazinecarboxamide (127) (Et3N, PhH, 20°C, 30 min 85%).505... [Pg.318]

Benzamido-2-pyrazinecarbonitrile 3-Benzamido-2-pyrazinecarboxamide 3-Benzoyl-5-bromo-2-pyrazinamine 2-Benzoyl-5-chloro-3-dimethylaminopyrazine 2-Benzoyl-3-chloropyrazine... [Pg.367]

Bromoanilino)-5-chloro-3-guanidinocarbonyl-2-pyrazinamine 5- Bromo-6-icobutyl-1 -hy droxy-... [Pg.377]

Chloro-5,6-dimethyl-2-pyrazinamine 2-Chloro-3,5-dimethylpyrazine 2-Chloro-3,6-dimethylpyrazine 2-Chloro-5,6-dimethylpyrazine 5-Chloro-3,6-dimethyl-2-pyrazinecarbonitrile 5-Chloro-1,4-dimethyl-2,3 (17/, 47/)-... [Pg.386]

Chloro-6-(A-ethyl-A-methylamino)-3-guamdinocarbonyl-2-pyrazinamine 2-Chloro-3-ethyl-5-methylpyrazine 5-Chloro-6-(A-ethyl-A-propylamino)-3-guamdinocarbonyl-2-pyrazinamine 5 - Chloro- 6- (1 - ethy lpropyl )ami no-3-guanidinocarbonyl-2-pyrazinamine 2-Chloro-3-ethylpyrazine... [Pg.388]

Chloro-3-methoxy-2-pyrazinamine 2-Chloro-3-methoxypyrazine 2-Chloro-5-methoxypyrazine 2-Chloro-6-methoxypyrazine 6-Chloro-3-methoxy-2-pyrazinecarbonitrile 6-Chloro-3-methoxy-2-pyrazinecarboxamide 2-Chloro-6-methylamino-3,5-diphenylpyrazine 2-Chloro-3-methylaminopyrazine 6-Chloro-3-methylamino-2-pyrazinecarboxamide 5-Chloro-6-methylamino-2,3-... [Pg.391]

Chloro-5-methyl-2-pyrazinamine 3-Chloro-6-methyl-2-pyrazinamine... [Pg.392]

See other pages where 5-Chloro-2-pyrazinamine is mentioned: [Pg.287]    [Pg.394]    [Pg.394]    [Pg.287]    [Pg.394]    [Pg.394]    [Pg.147]    [Pg.152]    [Pg.174]    [Pg.287]    [Pg.287]    [Pg.354]    [Pg.368]    [Pg.378]    [Pg.379]    [Pg.379]    [Pg.382]    [Pg.385]    [Pg.385]    [Pg.387]    [Pg.387]    [Pg.387]    [Pg.388]    [Pg.388]    [Pg.388]    [Pg.388]    [Pg.388]    [Pg.389]    [Pg.389]    [Pg.389]    [Pg.389]    [Pg.391]    [Pg.391]    [Pg.392]    [Pg.393]    [Pg.394]    [Pg.394]    [Pg.394]   
See also in sourсe #XX -- [ Pg.271 ]

See also in sourсe #XX -- [ Pg.271 ]



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2-Pyrazinamine

Pyrazinamines

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