Chlordene chlorohydrin

Microorganisms such as Nocardiopsis sp., an actinomycete, can metabolize cis- and trans-chlo-rdane to at least eight solvent-soluble substances, including dichlorochlordene, oxychlordane, hep-tachlor, heptachlor endo-epoxide, chlordene chlorohydrin, and 3-hydroxy-trans-chlordane (Beeman and Matsumura 1981). Based on studies of chlordane metabolism in animals, four metabolic pathways are proposed (Feroz and Khan 1979a WHO 1984 Nomeir and Hajjar 1987 USEPA 1988) ... 

The analyses involved the exposure of developed chromatograms to x-ray films followed by scraping of radioactive spots and quantifying them. Relative amounts of various compounds in the fractions are indicated on the righthand side against numbered spots. Spots A-6, B-4, and C-5 represent unchanged cis-chlordane A-7 was a mixture of dichloro-chlordene and oxychlordane. A-3, B-3, C-4, and D-4 represent chlordene chlorohydrin. A-2, B-2, C-2, and D-2 were complex spots with the heptachlor diol as the major compound. A-l, B-l, C-l, and D-l were polyhydroxy derivatives or conjugates. Identities of other spots are not known. Recoveries in fractions A, B, C, and D were, respectively, 60.1%, 0.6%, 2.2%, and 2.9% of the applied radiocarbon. 

Soil The actinomycete Nocardiopsis sp. isolated from soil extensively degraded pure cis- and /ra/3s-chlordane to dichlorochlordene, oxychlordane, heptachlor, heptachlor e/ c/o-epoxide, chlordene chlorohydrin, and 3-hydroxy-traas-chlordane. Oxychlordane slowly degraded to 1-hydroxy-2-chlorochlordene (Beeman and Matsumura, 1981). In Hudson River, NY sediments, the presence of adsorbed chlordane suggests it is very persistent in this environment (Bopp et al., 1982). The reported half-life in soil is approximately 1 yr (Hartley and Kidd, 1987). 

Chlordene chlorohydrin, see Chlordane Chlordene epoxide, see Heptachlor Chlorinated dibenzo-p-dioxin, see Pentachlorophenol Chlorinated dibenzo-p-dioxins, see PCB-1242, PCB-1254... 

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