Chitooligosaccharide-specific

The E. histolytica lectin specific for chitooligosaccharides is a 220 kDa plasma membrane glycoprotein that inhibits the attachment of amoebic tropozoites to layers of cultured MDCK cells [152,153]. 

FIGURE 29.3 Sophisticated catabolic mechanisms of chitooligosaccharides in vibrios. In earlier studies, many enzymes involved in the signaling pathway were cloned and characterized. 1, MV -diacetylchitobiose phosphorylase (ChbP) 2, glucosamine-specific kinase (GspK) 3, (l-glucosidase (BglA). 

Baureithel, K., Felix, G., and Boiler, T. 1994. Specific, high affinity binding of chitin fragments to tomato cells and membranes Competitive inhibition of binding by derivatives of chitooligosaccharides and a Nod factor of Rhizobium. J. Biol. Chem. 269 17931-17938. 

Zhang, X.F., Ding, C.L., Liu, H., et al., 2011. Protective effects of ion-imprinted chitooligosaccharides as uranium-specific chelating agents against the cytotoxicity of depleted uranium in human kidney cells. Toxicology 286, 75-84. 

Figure 6 The unsaturated acyl chains present on the chitooligosaccharide backbones of Nod factors contribute to host specificity of Rhizobium species. (A) In R. meliloti these are Ci6 2 (trans A2, cis A9) and Ci6 3 (trans A2, trans A4, cis A9) and in R. leguminosarum Ci8 4(trans A2, trans A4, trans A6, cis A9). (B) Three genes with homology to FAS components occur on a R. meliloti Bam HI fragment. Deletion analyses have established that the nodE and nodF genes are essential for synthesis of the unsaturated fatty acyl chains, but that nodG is not [43]. (C)...

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