Chirality directed self-assembly

Chirality-Directed Self-Assembly An Enabling Strategy for Ligand Scaffold Optimization... 

Chirality-Directed Self-Assembly Selective Formation of Neutral, Heteroleptic Zinc(ii) Complexes... 

Figure 9.6 Chirality-directed self-assembly of chiral bidentate SALs and bimetallic catalyst systems.

Fouquey, C. Lehn, J.-M. Levelut, A.-M. Molecular recognition directed self-assembly of supramolecular liquid crystalline polymers from complementary chiral components. Adv. Mater. 1990, 2, 254-257. 

Gulikkrzywicki T, Fouquey C, Lehn JM. Electron-microscopic study of supramolecular liquid-crystalline polymers formed by molecular-recognition-directed self-assembly from complementary chiral components. Proc Natl Acad Sci USA 1993 90 163-167. 

T. Gulik-Krzywicki, C. Fouquey, J.-M. Lehn, Electron Microscopic Study of Supramolecular Liquid Crystalline Polymers Formed by Molecular-Recognition-Directed Self-Assembly from Complementary Chiral Components , Proc. Natl. Acad. Sci. USA, 90, 163 (1993)... 

As part of an ongoing program focused on chirality in supramolecular systems [8, 39], it was noted that stereochemical aspects of H-bonding information may also be used to direct self-assembly processes. Racemic 12 produces a pleated ribbon comprised of doubly H-bonded components of alternating chirality, motif A. In contrast, optically pure 12 is predicted to form the cyclic hexamer B, provided the available H-bonding capacity is fully used... 

The racemic mixture of all four components LP2, LU2, DP2, and DU2 yielded long superhelices of opposite handedness that coexisted in the same sample, pointing to the occurrence of spontaneous resolution through chiral selection in molecular recognition-directed self-assembly of supramolecular liquid-crystalline polymers. Such chiral selection features of self-organized entities are of general significance in connection with the questions of spontaneous resolution and of chirality amplification. This was confirmed by subsequent studies on a variety of helical supramolecular polymers (see Chapters 2, 3, and 6). 

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