Chiral Recognition in Organometallic and Coordination Compounds

The chiral recognition ability of 4.2 was examined by two-phase liquid-liquid extraction experiments of racemic mixtures of amino acids and ester guests. Cram and coworkers developed an enantiomer-resolving machine based on such chiral corand receptors and found that the /f,/f-host was selectively able to extract the D-enantiomer of amino acids. 

The aim of this chapter is to discuss the recent examples of chiral recognition in organometallic and coordination compounds. Most of the examples presented are related to octahedral tris(bidentate) compounds with helical chirality. The homo-chiral 

Chirality in Transition Metal Chemistry Molecules, Supramolecular Assemblies and Materials H. Amouri and M. Gruselle 2008 John Wiley Sons,Ltd. ISBN 978-0-470-06053-7 

Chiral homodimeric soft ball capsule (4.3)2 from achiral component (4.3) bearing two different glycoluril residues (reprinted with kind permission of Springer Science and Business Media from reference page 32). 

Finally a brief introduction to chiral recognition of DNA (a chiral biomolecule) by optically pure octahedral metal complexes will be presented. 

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