Chiral Monophosphorus Ligands

Chiral monophosphorus ligands, in hydrogenation, 10, 16 Chiral nematic phase, calamitic mesogens, 12, 200 Chiral N,P ligands, in hydrogenation, 10, 17 Chiral phosphines... 

Highly Enantioselective or Not - Chiral Monodentate Monophosphorus Ligands in the Asymmetric Hydrogenation... 

The application of a mixture of a chiral and an achiral monophosphorus ligand for the rhodium catalyzed asymmetric hydrogenation of enamides was tested by Beller and coworkers [45]. By using a mixture of a chiral monophosphine 36a and an achiral ligand tris(4 methoxyphenyl)phosphine [P(4 MeOCf,H4)3] (1 1), the N (1 phenylvi nyl)acetamide (7a) was hydrogenated to amine 8a with 88% ee, but this enantios electivity is inferior to that obtained with single monophosphine 36a (93% ee). 

Komarov, I. V. Borner, A. Highly enantioselective or not —Chiral mono-dentate monophosphorus ligands in the asymmetric hydrogenation. Angew. Chem. Int. Edit. 2001, 40,1197-1200. 

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