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Chick embryo chorioallantoic membrane CAM assay

Aroylindoles bind to the colchicine site of p-tubulin, however, and in contrast to colchicine (1), vincristine (2a), nocodazole (13) or taxol (3), they showed no significant influence on the GTPase activity up to 10 pM [48,49]. In addition, angiogenesis in the chick embryo chorioallantoic membrane (CAM) assay was inhibited by D-64131 and analogue. Since 2-aroylindoles are easy to synthesise (Scheme 2), the role of the indole substitution pattern was studied in more detail. [Pg.729]

See other pages where Chick embryo chorioallantoic membrane CAM assay is mentioned: [Pg.244]    [Pg.24]    [Pg.1447]   
See also in sourсe #XX -- [ Pg.252 , Pg.253 , Pg.254 , Pg.255 , Pg.256 , Pg.257 , Pg.258 , Pg.259 , Pg.260 , Pg.261 ]



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