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Chemokine binding proteins limitations

SECRET domain VARV, ECTV, CPXV Secreted, protein domain fused to the TNFRs CrmB and CrmD, or expressed independently as three SCPs encoded by different genes, binds a limited set of CC and CXC chemokines, inhibits cell migration 42... [Pg.169]

Models also can assist in experimental design and the determination of the limits of experimental systems. For example, it is known that three proteins mediate the interaction of HIV with cells namely, the chemokine receptor CCR5, the cellular protein CD4, and the viral coat protein gpl20. An extremely useful experimental system to study this interaction is one in which radioactive CD4, prebound to soluble gpl20, is allowed to bind to cellular receptor CCR5. This system can be used to screen for... [Pg.44]

See other pages where Chemokine binding proteins limitations is mentioned: [Pg.82]    [Pg.192]    [Pg.120]    [Pg.172]    [Pg.365]    [Pg.369]    [Pg.2121]    [Pg.196]    [Pg.4]    [Pg.160]    [Pg.167]    [Pg.242]    [Pg.91]    [Pg.223]    [Pg.794]    [Pg.196]    [Pg.46]    [Pg.162]    [Pg.265]    [Pg.34]    [Pg.175]    [Pg.18]    [Pg.341]    [Pg.360]    [Pg.368]    [Pg.237]   
See also in sourсe #XX -- [ Pg.367 , Pg.368 ]



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