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Chemical Interactions with Biological Targets

Beyond successful modeling of important physicochemical dmg properties, there exist several examples in the literature that document the prime impact of H-bond [Pg.148]

Pharmacodynamics Biological effect of chemical interaction with target sites in the body. [Pg.314]

Biologically effective dose The amount of a deposited or absorbed chemical that reaches the cells or target site where an adverse effect occurs, or where that chemical interacts with a membrane surface (USEPA, 1992a, 1997b REAP, 1995). [Pg.391]

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Biological targets

Chemical interaction

Target chemicals

Target-targeter interaction