Chemical arrays inhibitor discovery

LIGAND AND INHIBITOR DISCOVERY USING CHEMICAL ARRAYS AND ITS APPLICATION TO CHEMICAL GENETIC STUDY... 

Schreiber gave another example where he successfully employed diver-sify-oriented synthesis for the discovery of transcription factor inhibitors (Koehler, Shamji, and Schreiber, 2003). Khersonsky and coworkers linked forward chemical genetics techniques with chemical microarrays. After phenotypic screening, triazine core-containing affinity matrices as micro-arrays were used (Khersonsky et al., 2003 Khersonsky and Chang, 2004). 

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