Chemical and biological synthesis

Tetr 39 2323 (1983) (Recent Advances in the Preparation and Synthetic Applications of Oxiranes) 43 3309 (1987) (Synthetic Routes to Tetrahydrofuran, Tetrahydropyran, and Spiroketal Units of Polyether Antibiodcs and a Survey of Spiroketals of Other Natural Products) SO 8885 (1994) (Chemical and Biological Synthesis of Chiral Epoxides)... 

Figure 1 A comparison of the chemical and biological synthesis of the antibiotic erythromycin A.

This volume of Advances in Polymer Science is an attempt to provide an overview of the state of the art in the area of peptide hybrid polymers. The five articles in this volume cover a broad range of topics, from chemical and biological synthesis, to solution and solid-state self-assembly, to medical applications. 

A second strategy that avoids the synthetases combines both chemical and biological synthesis. Chemical aminoacylation methods were introduced by Hecht and co-workers in the late 1970s (153) and have since been exploited by a variety of other investigators (154-157). In these strategies, the nonnatural amino acid is... 

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