Chelerythrine from Chelidonium majus

Use Chelerythrine (1) is the most active alkaloid from Chelidonium majus (swallowwort), topically it has an irritating effect, taken orally, it causes vomiting, gas-... 

Chelerythrine, C2iHi,04N. H2O. (Items 4, 5, 6, 7, 43, 46, 60 list, p. 169). This base was isolated by Probst from the root of Chelidonium majus. It was probably first obtained in a pure state by Konig and Tietz, from the root of Sanguinaria canadensis. A process for the separation and purification of the alkaloids of Chelidonium majus roots is given by Schmidt and Selled... 

Fig. 36.3 Chemical structures of sanguinarine and coptisine and CZE separation of seven alkaloids in an extract of Chelidonium majus L. Peaks (7) sanguinarine, (2) coptisine, (3) chelerythrine, (4) stylopine, (5) chelidtmme, (6) protopine, (7) allocryptopine, and (x) unknown component. Conditions 20 mM phosphate buffer, pH 3.1. Separation capillary 75 pm, i.d. uncoated fused silica, 50 cm in length (40 cm effective length). Applied voltage 16 kV. Light-emitting-diode-induced fluorescence (LED) excitation wavelength 280 nm (Modified from reference [14])...

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