Charcoal intestinal dialysis

Critchley JA, Critchley LA. Digoxin toxicity in chronic renal failure treatment by multiple dose activated charcoal intestinal dialysis. Hum Exp Toxicol 1997 16(12) 733-5. 

Antiflatulents are used for die relief of painful symptoms of excess gas in the digestive tract. These drugs are useful as adjunctive treatment of any condition in which gas retention may be a problem (ie, postoperative gaseous distention, air swallowing, dyspepsia, peptic ulcer, irritable colon, or diverticulosis). In addition to its use for tiie relief of intestinal gas, charcoal may be used in the prevention of nonspecific pruritus associated with kidney dialysis treatment and as an antidote in poisoning. Simethicone is in some antacid products, such as Mylanta liquid and Di-Gel liquid. 

Gastric lavage should be carried out immediately if oral consumption is suspected. In order to hasten intestinal elimination charcoal tablets should be administered at 4-hr intervals with sodium sulfate as laxative. To activate the antimony the chelating agent Sulfactin must be administered intramuscularly and also about every 4 hr. Chelated antimony is excreted renally and is readily dialyzed. Hence continuous hemodialysis can be carried out if necessary. The administration of Sulfactin must be continued throughout the whole dialysis. The intravenous administration of lasix with a balanced substitution of electrolyte solutions to force diuresis is also promising in cases of very high levels of Sb intoxication [33]. 

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