Chara globularis

Anthoni U, Nielsen PH, Smith-Hansen L, Wium-Andersen S, Christophersen C (1987) Charamin, a quaternary ammonium ion antibiotic from the green alga Chara globularis. J Org Chem 52 694-695... 

White and coworkers used trans Addition of bromine and (-)-l-bomeol to 3,4-dihydro-2//-pyran to afford the stereoisomeric bomyl bromotetrahydropyranyl ethers (3) and (4 Scheme 44) which are employed in an enantioselective total synthesis of (-)-monic acid C (Scheme 5).10 A simple synthesis of 4-methylthio-l,2-dithiolane, the photosynthesis inhibitor of the green alga Chara globularis (Scheme 45),83 exploits the observation that allylic sulfides undergo rearrangement on addition of bromine.84 Block and Naganathan employed the trans addition of bromine to 4-thioacetoxycyclopentene as a key... 

Scheme 1. Structures of synthetic 3-azetidinol [1] and the antibiotic charamin [2] from the freshwater green alga Chara globularis.

From our own work studies of synthetic 3-azetidinol [1], part of the structure of the antibacterial agent charamin (4-azoniaspiro[3,3]heptane-2,6-diol, 2) from the green characean alga Chara globularis (1), serve to illustrate the kind of data and instrumentation available in modem investigations. The crystal and molecular struc-... 

Scheme 20. Structures of nereistoxin (4-dimethylamino-l,2-dithiolane) from a marine worm and of charatoxin I (ChTx 1,4-methylthio-l,2-dithiolane) and charatoxin II (ChTx II, 5-methylthio-l,2,3-trithiane) from the freshwater green alga Chara globularis.

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