Chamigrenes, halogenated

Furusaki, A., Hashiba, N. and Kurosawa, E. 1979. The structures and absolute stereochemistry of two halogenated chamigrenes from the red alga Laurencia majuscula Harvey. Tetrahedron Lett. 879-882. 

The halogenated spiro-chamigrene, and related metabolites represent a huge class of marine natural products, mainly from Laurencia seaweeds. The initial survey documented 85 examples (7). 

Guella G, Chiasera G, Pietra F (1992) Conformational Studies of Marine Polyhalogenated a-Chamigrenes Using Temperature-Dependent NMR Spectra. Inverted Chair and Twist-Boat Cyclohexane Moieties in the Presence of an Axial Halogen Atom at C(8). Helv Chim Acta 75 2026... 

During our work on active metabolites from starfish we have isolated from Astropecten indicus three novel steroidal glycosides named as indicoside A (26). B (27) and C (28). The red alga Laurencia pinnatifida yielded three new halogenated sesquiterpenoids pinnatificine (29) pinnatifidone (30) and 1(1 4(3,10d tr ibromo-3-chloro-7(14)-ene-a-chamigrene (31). ... 

Gonzalez, A.G., Darias, J., Diaz, A., Fourneron, J.D., Martin, J.D., and Perez, C. (1976a) Evidence for the biogenesis of halogenated chamigrenes from the red alga Laurencia obtusa. Tetrahedron Lett., 17, 3051-3054. 

Howard, B.M. and Fenical, W. (1975) Structures and chemistry of two new halogen-containing chamigrene derivatives from Laurenda. Tetrahedron Lett., 16,1687—1690. 

Sakai, R Higa, T Jefford, C.W., and Bernardinelli, G. (1986) The absolute configurations and biogenesis of some new halogenated chamigrenes from the sea hare Aplysia dactylomela. Helv. Chim. Acta, 69,91-105,... 

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