Chain transfer agent secondary functionalization

The trithiocarbonates, such as RT-11 and RT-12 in Scheme 3.8 are another type of difunctional transfer agent, and can be used in the RAFT polymerization of monomer A. One way to confirm the presence of an active trithiocar-bonate group located in the center is to cleave the polymer chains at the trithiocarbonate function. This can be achieved in the presence of mild nucleophiles such as primary or secondary amines. Generally, the molecular weight of... 

Besides functional initiators, a wide range of functional terminating agents have been utilized for the preparation of functional poly(2-oxazoline)s, including deprotonated carboxylic acids [184, 185], amines [185, 186], and deprotonated thiols (Scheme 8.27) [187]. The termination with primary amines can be complicated by the formation of secondary amines that can react with a second polymer chain after proton transfer to the unreacted primary amines. 

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