Chain cleavage expression

The transport of cholesterol to, and its side-chain cleavage in, the mitochondria are the most important steps in the hormonal control of steroidogenesis. The enzymatic activities in the endoplasmic reticulum are also under hormonal control. However, expression of hormonal effects in this compartment requires several hours and is therefore part of the chronic, trophic effects of LH [3,4,32],... 

Cholesterol side-chain cleavage gene expression in theca cells augmented transcriptional regulation and mRNA stability in polycystic ova-rysyndrome. PLoS One 7 e48963... 

By considering both non-catalysed and self-catalysed hydrolysis reactions, the chain cleavage rate can be expressed according to Pan (Han et al., 2010 Wang et al., 2008) as ... 

All classes of RNA transcripts must be processed into mature species. The reactions include several types Nucleolytic cleavage, as in the separation of the mature rRNA species from the primary transcript of RNA polymerase I action Chain extension (non-template-directed), as in the synthesis or regeneration of the common CCA sequence at the 3 end of transfer RNAs or of PolyA at the 3 end of mRNAs and Nucleotide modification, for example, the synthesis of methylated nucleotides in tRNA or rRNA. These reactions are a feature of both prokaryotic and eukaryotic gene expression, and the biological consequences are diverse. For example, modified nucleotides can affect the way in which a tRNA recognizes different codons. 

Virtually all proteins expressed in cells undergo processing to remove the N-terminal methionine residue encoded by the start codon , ATG. Cleavage of this initiation methionine from newly formed polypeptide chains is catalyzed by the enzyme methionine aminopeptidase (equation 9). 

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