CFC alternatives and new catalytic methods of synthesis

Chlorofluorocarbons, pioneered by the American chemist Thomas Midgley (1889-1944) who was also responsible for pioneering the use of lead alkyls as anti-knock agents, were regarded for many years as ideal 

Depletion of stratospheric O3 by CCI2F and other CFCs was summarised in 1987, the year of the first Montreal Protocol on Substances that Deplete the Ozone Layer, by the reactions 

C2 compounds CF3CH2F (HFC-134a), CF3CHF2 (HFC-125) C3 compounds CF3CHFCF3 (HFC-227ea)  

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Webb G, Winfield JM. In Clark JH, editor. Chemistry of waste minimization. Glasgow Blackie Academic and Professional 1995. p. 222-46 [chapter 8, CFC Alternatives and New Catalytic Methods of Synthesis]. 

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